RestoriX^®

Product Information

Our human body is made up of trillions of cells. They are the basic building blocks of life. Cells have specific tasks to perform and they work together to enable the body to meet its basic needs. These cellular processes require energy to function. However, as we age, cellular energy production in our body decreases¹.

NAD+ THE MOLECULE OF YOUTH

Nicotinamide adenine dinucleotide (NAD+) is a coenzyme that is present naturally in every cell of our body and is essential to life. It is known as the molecule of youth due to its role in cellular energy production and its ability to regulate the genes of aging¹. Unfortunately, as we grow older, the NAD+ levels in our body declines¹.
RestoriX^® contains nicotinamide which is a precursor of NAD+ to boost the NAD+ cellular levels in the body. Daily supplementation of RestoriX^® combats the ravages of aging!

SUPPORT ENERGY PRODUCTION

Mitochondria are powerhouses of our cells. They are empowered by NAD+ in the production of cellular energy for the sustenance of life. As the level of NAD+ declines with age, mitochondria function is impaired which results in reduced amount of surviving healthy mitochondria². This vicious cycle of the depletion of mitochondria which results in metabolic energy deficiency is evident in the physical symptoms of aging such as chronic fatigue and weakness. NAD+ is crucial in the maintenance of functional mitochondria in preserving cellular energy reserve to ensure the body to be in a constant state of health.

“TURN OFF” AGING GENES

Sirtuins are enzymes that have the ability to regulate the genes of aging³. These enzymes are dependent on NAD+ for their function as NAD+ directly activates them to switch off genes that promote aging^4,5. Therefore, boosting the level of NAD+ is intimately related to longevity.

DNA CELL REPAIR

Poly-ADP-ribose polymerase-1 (PARP-1) is an enzyme that detects DNA damage and initiates DNA repair⁶. The function of PARP-1 is important as the accumulated replication of damaged DNA would lead to progressive functional decline in many tissues in our body which contributes to the process of aging⁶. For PARP-1 to exert its effect, it requires NAD+ as its sole substrate^6,7. Thus, replenishment of NAD+ via supplementation is important in the prevention of damaged DNA replication and the initiation of DNA repair to protect cellular integrity⁷. In addition, resveratrol is a potent antioxidant which protects cells and deters cell damage as well, complementing the actions of NAD+.

Ingredients

Serving Size: 1-2 tablets
Servings Per Container: Up to 60
Amount Per Tablets:

Directions

How to use

Take 1-2 tablets every morning with or without food or as recommended by your physician.

Storage

Store in cool, dry place. Keep out of reach of children. Use only if bottle is sealed.

Precautions

Do not take RestoriX^® if you are pregnant, breastfeeding, trying to conceive or under 18 years of age.
If you have any medical conditions, please consult your physician prior to use.

Science

1. Imai S, Guarente L. NAD+ and sirtuins in aging and disease. Trends in Cell Biology. 2014;24(8):464-471.
2. Croteau D, Fang E, Nilsen H, Bohr V. NAD+ in DNA repair and mitochondrial maintenance. Cell Cycle. 2017;16(6):491-492.
3. Guarente L. Linking DNA Damage, NAD+/SIRT1, and Aging. Cell Metabolism. 2014;20(5):706-707.
4. Belenky P, Racette F, Bogan K, McClure J, Smith J, Brenner C. Nicotinamide Riboside Promotes Sir2 Silencing and Extends Lifespan via Nrk and Urh1/Pnp1/Meu1 Pathways to NAD+. Cell. 2007;129(3):473-484.
5. Longo V, Kennedy B. Sirtuins in Aging and Age-Related Disease. Cell. 2006;126(2):257-268.
6. Javle M, Curtin N. The role of PARP in DNA repair and its therapeutic exploitation. British Journal of Cancer. 2011;105(8):1114-1122.
7. Surjana D, Halliday G, Damian D. Role of Nicotinamide in DNA Damage, Mutagenesis, and DNA Repair. Journal of Nucleic Acids. 2010;2010:1-13.
8. Yoshinori Okada, Mizue Okada. Quercetin, caffeic acid and resveratrol regulate circadian clock genes and aging related genes in young and old human lung fibroblast cells. Molecular Biology Reports. 2020;47:1021–1032.
9. Ajay Sharma, Dharambir Kashyap, Katrin Sak, Hardeep Singh Tuli, Anil K Sharma. Therapeutic charm of quercetin and its derivatives: a review of research and patents. Pharmaceutical patent analyst . 2018;7(1):15–32.
10. Zehao Jing, Zhuorun Wang, Xiujie Li, Xintao Li, Tingting Cao, Yue Bi, Jicheng Zhou, Xu Chen, Deqin Yu, Liang Zhu, Shuzhuang Li. Protective Effect of Quercetin on Posttraumatic Cardiac Injury. Scientific Reports. 2016;6(30812):1-10.
11. Asma Hoseini, Gholamreza Namazi, Alireza Farrokhian, Željko Reiner, Esmat Aghadavod, Fereshteh Bahmani, Zatollah Asemi. The effects of resveratrol on metabolic status in patients with type 2 diabetes mellitus and coronary heart disease. The Royal Society of Chemistry Food Funct. 2019;10:6042–6051.
12. Pankaj K. Bagul, A.K. Dinda, Sanjay K. Banerjee. Effect of resveratrol on sirtuins expression and cardiac complications in diabetes. Biochemical and Biophysical Research Communications. 2015; 468:221-227.

FAQ

Who is RestoriX^® suitable for?

RestoriX^® is most suitable for men and women who:
– are in their 30s or older
– wish to boost their energy levels to combat end-of-day fatigue
– wish to maintain an active lifestyle

What is nicotinamide?

Nicotinamide is a form of vitamin B3. It is the primary precursor of nicotinamide adenine dinucleotide (NAD+), an essential coenzyme in cellular repair and energy production.

What is the difference between RestoriX^® and MetaboliX^® Plus?

Although both products contain nicotinamide which is essential for cellular repair and energy production, MetaboliX^® Plus has the added ingredient of boswellic acids for people who suffer from joint discomfort and inflammation caused by mild osteoarthritis.

How would I know if RestoriX^® is effective for me?

By taking RestoriX^®, it is an investment for your well-being as it works to improve the health of your cells. Bearing in mind that every individual’s physiology make-up is unique, some may experience a positive difference in energy level throughout the day within 3-4 weeks, while others may take longer.

Product Reviews (2)

Roland T, 76

I was initially sceptical about the RestoriX that my daughter gave me as I was not suffering from any health issues and didn’t feel the need to take any supplements. However, just to humour her, I agreed to give it a try. I didn’t feel any difference at first, but after two weeks, I actually felt much more alert and energised overall.

Jenny L, 60

I tried RestoriX on the recommendation of my daughter. Luckily I don’t suffer from chronic pain but as I’ve gotten older I’ve started to feel my energy levels declining, especially on the weekday afternoons. Soon after including RestoriX into my morning ritual, I no longer have any midday lull! It keeps me going throughout my busy day.